Inferior Colliculus

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Inferior colliculus microcircuits

Manuel S. Malmierca and Eric D. Young* 1 Auditory Neurophysiology Unit, Laboratory for the Neurobiology of Hearing, Institute of Neuroscience of Castilla y León, University of Salamanca, Salamanca, Spain 2 Department of Cell Biology and Pathology, Faculty of Medicine, University of Salamanca, Salamanca, Spain 3 Neural Encoding Laboratory, Biomedical Engineering, Johns Hopkins University, Baltim...

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Serotonin in the inferior colliculus.

It has been recognized for some time that serotonin fibers originating in raphe nuclei are present in the inferior colliculi of all mammalian species studied. More recently, serotonin has been found to modulate the responses of single inferior colliculus neurons to many types of auditory stimuli, ranging from simple tone bursts to complex species-specific vocalizations. The effects of serotonin...

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Efferent pathways modulate hyperactivity in inferior colliculus.

Animal models have demonstrated that mild hearing loss caused by acoustic trauma results in spontaneous hyperactivity in the central auditory pathways. This hyperactivity has been hypothesized to be involved in the generation of tinnitus, a phantom auditory sensation. We have recently shown that such hyperactivity, recorded in the inferior colliculus, is still dependent on cochlear neural outpu...

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Spike-frequency adaptation in the inferior colliculus.

We investigated spike-frequency adaptation of neurons sensitive to interaural phase disparities (IPDs) in the inferior colliculus (IC) of urethane-anesthetized guinea pigs using a stimulus paradigm designed to exclude the influence of adaptation below the level of binaural integration. The IPD-step stimulus consists of a binaural 3,000-ms tone, in which the first 1,000 ms is held at a neuron's ...

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Tinnitus-Related Changes in the Inferior Colliculus

Tinnitus is highly complex, diverse, and difficult to treat, in part due to the fact that the underlying causes and mechanisms remain elusive. Tinnitus is generated within the auditory brain; however, consolidating our understanding of tinnitus pathophysiology is difficult due to the diversity of reported effects and the variety of implicated brain nuclei. Here, we focus on the inferior collicu...

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ژورنال

عنوان ژورنال: Nature Precedings

سال: 2008

ISSN: 1756-0357

DOI: 10.1038/npre.2008.2033